glucosamine hydrochloride - Swedish translation – Linguee
MR2004-183 - DTU Orbit
The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. Structure. Valinomycin is a dodecadepsipeptide, that is, it is made of twelve alternating amino acids and esters to form a macrocyclic molecule. The twelve carbonyl groups are essential for the binding of metal ions, and also for solvation in polar solvent.
2. The structure of salinomycin, a new member of the polyether ant ibiotics. Kinashi H. Tetrahed. 2016-03-01 For a structural comparison, salinomycin·Na, SY-1·Na, and 18,19-dihydro SY-1·Na were modeled using the X-ray structure of SY-1·Na as the initial geometry. (1976).
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1633-1640. PDF | On Oct 15, 1975, H. Kinashi and others published Studies on the ionophorous antibiotics.
glucosamine hydrochloride - Swedish translation – Linguee
The structure of salinomycin, a new member of the polyether ant ibiotics. Kinashi H. Tetrahed. 2016-03-01 For a structural comparison, salinomycin·Na, SY-1·Na, and 18,19-dihydro SY-1·Na were modeled using the X-ray structure of SY-1·Na as the initial geometry.
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Name. Salinomycin.
The ionophore salinomycin exerts selective activity against cancer stem cells.
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Synonyms. (2R)-2- ( (5S)-6- {5- [ (10S,12R)-2- ( (6S,5R)-5-Ethyl-5-hydroxy-6-methylperhydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro [4.1.5.3]pentadec-13-en-9-yl] (1S,2S,3S,5R)-2-hydroxy-1,3-dimethyl-4-oxoheptyl}-5-methylperhydro-2H-pyran-2-yl)butanoic acid. Molecular Structure. Synthetic strategies for modification of each of the directly accessible functional groups of salinomycin are presented and the resulting library of analogues was investigated to establish structure–activity relationships, both with respect to cytotoxicity and phenotype selectivity in breast cancer cells. 20-O-Acylated derivatives stand out by exhibiting both improved selectivity and activity. 2017-04-01 · The X-ray structure of salinomycin-salicylhydroxamic acid conjugate (11b). The antiproliferative activities of salinomycin-hydroxamic acid conjugates were evaluated in HT-29 colorectal cancer, HGC-27 gastric cancer and triple-negative MDA-MB-231 breast cancer cells using MTT assay ( Table 1 ).